Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC121H204N34O32

DescriptionStandard

        GLASLLGKALKAGLKIGTHFLGGAPQQ
    

Molecular Weight2647.12 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)2.84

Net Charge (pH 7.4) 2.59

Charge Density (pH 7.0) 0.1053

GRAVY Index0.37

Hydrophobic Moment 0.62

Boman Index0.28

Instability Index12.89

Aliphatic Index 115.93

Aromaticity 0.0370

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1044.51

LogP -9.80

H-bond Donors 35.0

H-bond Acceptors 36.0

Rotatable Bonds 90.0

Heavy Atoms 187.0

Ring Count 3.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0096366 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0146105 VERIFIED: NO

Provenance & Taxonomy

OrganismXenopus ruwenzoriensis [Animal]

FamilyGastrin cholecystokinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0251714 VERIFIED: YES

Provenance & Taxonomy

OrganismXenopus clivii [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0276044 VERIFIED: NO

Provenance & Taxonomy

OrganismXenopus laevis [Animal] [Animal]; Xenopus ruwenzoriensis [Animal]

Tax ID8355

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone

TargetB cell line, BD11

RECORD: Rec_0341088 VERIFIED: YES

Provenance & Taxonomy

OrganismXenopus laevis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)