Peptide Database

Peptide NameT51-R9

Function Ontology

Immunology ▸ Cytokine / receptor signaling modulation ▸ TLR inhibition

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC110H204N48O23S

DescriptionStandard

        AIVKLTVYACIRRRRRRRRR
    

Molecular Weight2599.17 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)9.78

Net Charge (pH 7.4) 9.58

Charge Density (pH 7.0) 0.4892

GRAVY Index-0.95

Hydrophobic Moment 0.42

Boman Index-0.83

Instability Index258.73

Aliphatic Index 97.50

Aromaticity 0.0500

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1239.80

LogP -12.14

H-bond Donors 52.0

H-bond Acceptors 34.0

Rotatable Bonds 91.0

Heavy Atoms 182.0

Ring Count 1.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0054107 VERIFIED: YES

Provenance & Taxonomy

OrganismOrthopoxvirus vaccinia [Virus]

FamilyP13/A52R-derived

Tax ID10245.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Anti-inflammatory TLR inhibitor

TargetCpG- or LPS-stimulated RAW264.7 macrophage assays