Peptide Database

Peptide NameBeta-defensin 129

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length173 amino acids

Chemical FormulaC850H1384N230O244S12

DescriptionStandard

        MKLLFPIFASLMLQYKVNTEFIGLRRCLMGFGRCRDHCNVDEKEIQKCKMKKCCVGPKVVKLIKNYLQYGTPNVLNEDVQEMLKSAKNSSAVIQRKHILSVLPQIKSTSFFANTNFVIIPNATPMNSAIISTVTPGQITYTAASTKSNIKESRDSATASPPPAPPPPNTLPTP
    

Molecular Weight19114.26 Da

Isoelectric Point (pI)9.64

Net Charge (pH 7.0)11.62

Net Charge (pH 7.4) 11.17

Charge Density (pH 7.0) 0.0671

GRAVY Index-0.18

Hydrophobic Moment 0.73

Boman Index0.02

Instability Index38.48

Aliphatic Index 83.41

Aromaticity 0.0636

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7591.80

LogP -88.32

H-bond Donors 260.0

H-bond Acceptors 270.0

Rotatable Bonds 628.0

Heavy Atoms 1336.0

Ring Count 29.0

Amide Bonds 191.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0331288 VERIFIED: NO

Provenance & Taxonomy

OrganismHylobates lar [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence