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MYP_137934
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Basic Information
TPAEDFMRF-amide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Standard
9 amino acids
C50H72N12O15S
Standard
Sequence
TPAEDFMRF
Physicochemical Analysis
1113.24 Da
4.37
-1.60
-1.79
-0.1775
-0.50
0.62
-0.05
34.93
11.11
0.2222
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
444.06
-2.98
15.0
15.0
33.0
78.0
3.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0114925 VERIFIED: NO
Provenance & Taxonomy
Drosophila melanogaster [Animal]
FMRFamide related peptide
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
RFamide Neuropeptide Neuromodulator
Evidence URLhttps://www.uniprot.org/uniprotkb/FMRF_DROME/entry
RECORD: Rec_0133544 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
TPAEDFMRF-amide
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Neuromodulator Myotropic Receptor modulation
Mammalian: 7.2 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for TPAEDFMRF-amide (Drosophila melanogaster): PMID 12171930 PMID12171930 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12171930/
RECORD: Rec_0375566 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
FMRFamide-like peptide
7227.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Cardioactive Neuromodulatory
Drosophila melanogaster heart
Cardiac contractility assay
PaperPMID 24069424. Drosophila FMRFamide peptides (including TPAEDFMRFamide) modulate cardiac contractility via FMRFa-R. PMID24069424 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24069424/
RECORD: Rec_0409307 VERIFIED: NO
Provenance & Taxonomy
Drosophila melanogaster [Animal]
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide