Peptide Database

Peptide NameThiostrepton (Alaninamide) (Bryamycin) (Gargon) (Thiactin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC313H506N80O119S8

DescriptionStandard

        MDATAIHERWSVMSNASIGQEIGVEGLTGLDVDALEISDYVDETLLDGEDLTVTMIASASCTTCICTCSCSS
    

Molecular Weight7550.35 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-12.44

Net Charge (pH 7.4) -12.79

Charge Density (pH 7.0) -0.1728

GRAVY Index0.31

Hydrophobic Moment 0.41

Boman Index0.18

Instability Index49.54

Aliphatic Index 93.47

Aromaticity 0.0278

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3171.01

LogP -39.63

H-bond Donors 116.0

H-bond Acceptors 116.0

Rotatable Bonds 250.0

Heavy Atoms 520.0

Ring Count 4.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0204291 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptomyces azureus [Bacterium]

FamilyThiocillin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic

TargetNo Target Organism Found