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MYP_137849
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Basic Information
Rp-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
18 amino acids
C104H184N28O21
Standard
Sequence
ALYKKFKKKLLKSLKRLG
Physicochemical Analysis
2162.75 Da
10.82
7.79
7.59
0.4327
-0.59
0.86
-0.30
5.06
113.89
0.1111
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
842.52
-3.13
31.0
29.0
82.0
153.0
2.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001998 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Cryptococcus species
PMID18712851 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18712851/
RECORD: Rec_0023534 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 6743769 B1 Evidence URLhttps://patents.google.com/patent/US6743769B1/en PatentUS 6743769 B1
RECORD: Rec_0046725 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
Staphylococcus aureus, S. typhimurium, Escherichia coli
PaperSynthetic peptides that exert antimicrobial activities in whole blood and blood-derived matrices.
RECORD: Rec_0047276 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
RP
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Host-defense peptide Antiparasitic Antileishmanial Anti-Trypanosoma cruzi
Leishmania infantum chagasi MHOM/BR/00/1669
12.5 mg/kg
Microscopy (Giemsa staining)
PMID22123683 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22123683/
RECORD: Rec_0055503 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Salmonella
PMID18712851 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18712851/
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