Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length82 amino acids

Chemical FormulaC437H691N107O120S3

DescriptionStandard

        MRTKQVPVLWAFVLLWNLYISSSQTVYPGIKARITQRALDYGVQVGTKVMEDMAKEIVIPDLKGSESLEFLKIDYVKYNFSK
    

Molecular Weight9460.00 Da

Isoelectric Point (pI)9.26

Net Charge (pH 7.0)2.50

Net Charge (pH 7.4) 2.26

Charge Density (pH 7.0) 0.0305

GRAVY Index0.01

Hydrophobic Moment 0.68

Boman Index0.09

Instability Index22.92

Aliphatic Index 103.29

Aromaticity 0.1220

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3679.88

LogP -25.01

H-bond Donors 128.0

H-bond Acceptors 126.0

Rotatable Bonds 316.0

Heavy Atoms 667.0

Ring Count 15.0

Amide Bonds 87.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0071863 VERIFIED: NO

Provenance & Taxonomy

OrganismPeromyscus maniculatus bairdii [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence