Peptide Database

Peptide NameUnnamed

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC196H301N57O56S2

DescriptionStandard

        QLNFSAGWGRRYADPNADPMAFLYRLIQIEARKLAGCSD
    

Molecular Weight4415.96 Da

Isoelectric Point (pI)8.18

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.53

Charge Density (pH 7.0) 0.0194

GRAVY Index-0.37

Hydrophobic Moment 0.62

Boman Index-0.04

Instability Index26.85

Aliphatic Index 75.38

Aromaticity 0.1282

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1843.43

LogP -17.35

H-bond Donors 65.0

H-bond Acceptors 59.0

Rotatable Bonds 142.0

Heavy Atoms 311.0

Ring Count 8.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0034754 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0159318 VERIFIED: NO

Provenance & Taxonomy

OrganismLocusta migratoria [Animal]

FamilyAKH/HRTH/RPCH

Tax ID7004

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Other ModsTrp8 Amidation

Bio-Activity Profile

Function

Neuropeptide Invertebrate neurohormone Metabolic

RECORD: Rec_0354006 VERIFIED: YES

Provenance & Taxonomy

OrganismLocusta migratoria [Animal]

FamilyAdipokinetic prohormone type

Tax ID7004

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Disulfide37-37

Other Mods8:Tryptophan amide

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour