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MYP_137732
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Basic Information
RTD-5
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
18 amino acids
C80H148N30O19S6
Standard
Sequence
GICRCLCRRGVCRCICVL
Physicochemical Analysis
2026.61 Da
9.01
3.70
3.41
0.2056
1.18
0.59
-0.02
38.34
118.89
0.0000
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
805.62
-7.97
37.0
29.0
67.0
135.0
0.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0171809 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
PaperPubMed PMID: 21084627 PMID21084627 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21084627/
RECORD: Rec_0191711 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0211343 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID21084627 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21084627/
RECORD: Rec_0234343 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus 502a, Escherichia coli ML 35
PaperRhesus macaque {theta}-defensin isoforms: expression, antimicrobial activities, and demonstration of a prominent role in neutrophil granule microbicidal activities
RECORD: Rec_0315130 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
PMID21084627 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21084627/
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