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MYP_137729
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Basic Information
Pseudin-2
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
24 amino acids
C122H202N36O32
Standard
Sequence
GLNALKKVFQGIHEAIKLINNHVQ
Physicochemical Analysis
2685.13 Da
9.70
1.93
1.62
0.0806
-0.01
0.72
0.12
-2.96
130.00
0.0417
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1120.79
-8.98
36.0
36.0
94.0
190.0
3.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0080422 VERIFIED: YES
Provenance & Taxonomy
Pseudis paradoxa [Animal]
Pseudin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
50.0 μM
HC50
PaperD. Juretic et al. / Journal of Chemical Information and Modeling 49 (2009) 2873-2882. Computational design of highly selective antimicrobial peptides Evidence URLhttps://www.uniprot.org/uniprotkb/P83189/entry
RECORD: Rec_0081290 VERIFIED: YES
Provenance & Taxonomy
Pseudis paradoxa [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
PaperPubMed PMID: 11689009 PMID11689009 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11689009/
RECORD: Rec_0087940 VERIFIED: YES
Provenance & Taxonomy
Paradoxical frog [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID11689009 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11689009/
RECORD: Rec_0104846 VERIFIED: YES
Provenance & Taxonomy
Pseudis paradoxa [Animal]
Pseudin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus Sens 8325.4 [
250 μg/mL
MBC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
RECORD: Rec_0110896 VERIFIED: YES
Provenance & Taxonomy
Pseudis paradoxa [Animal]
Pseudin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa 26228 [
256 μg/mL
MIC
PMID31102497 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31102497/
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