Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC455H725N129O132S10

DescriptionStandard

        MKILCIFMVFVFTVSCGPADPQKKIREALVRKRECYLVRGSCKTKCNTWEYVYNHCDTEPCCVVREYIRPQEVTTISTTTHKNANSHSNI
    

Molecular Weight10435.06 Da

Isoelectric Point (pI)8.85

Net Charge (pH 7.0)4.69

Net Charge (pH 7.4) 4.18

Charge Density (pH 7.0) 0.0521

GRAVY Index-0.29

Hydrophobic Moment 0.61

Boman Index-0.07

Instability Index40.90

Aliphatic Index 71.33

Aromaticity 0.0889

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4237.60

LogP -42.78

H-bond Donors 157.0

H-bond Acceptors 150.0

Rotatable Bonds 342.0

Heavy Atoms 726.0

Ring Count 16.0

Amide Bonds 96.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0083169 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Tax ID9986

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence