Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length171 amino acids

Chemical FormulaC829H1323N239O234S9

DescriptionStandard

        MSPSIVKRCLVGAVLAIAATLPGFQSLHTSVEGLKLIADFEGCRLQPYQCSAGVWTDGIGNTSGVVPGKSITERQAAQGLINNVLLTEKRIEACLQVKPPQHVYDALISIGFNVGTGAICRSTMVSYINRQQWWKACNQLPRWVYVNGQWNKGLENRRARELAWCLKGAGA
    

Molecular Weight18670.42 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)7.62

Net Charge (pH 7.4) 7.17

Charge Density (pH 7.0) 0.0445

GRAVY Index-0.01

Hydrophobic Moment 0.69

Boman Index0.08

Instability Index46.65

Aliphatic Index 94.68

Aromaticity 0.0760

Extinction Coeff. Reduced 38960.00

Extinction Coeff. Oxidized 39335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7607.91

LogP -78.16

H-bond Donors 270.0

H-bond Acceptors 253.0

Rotatable Bonds 613.0

Heavy Atoms 1311.0

Ring Count 28.0

Amide Bonds 190.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0220180 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage ST13-OXA48phi12.1 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic