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MYP_137695
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Basic Information
Angiotensin I converting enzyme inhibitior 2
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
3 amino acids
C25H27N5O4
Standard
Sequence
AWW
Physicochemical Analysis
461.51 Da
5.57
-0.20
-0.39
-0.0680
0.00
0.20
0.75
6.67
33.33
0.6667
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
153.10
1.84
6.0
4.0
9.0
34.0
4.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0051203 VERIFIED: YES
Provenance & Taxonomy
Rachycentron canadum [Animal]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
9.40 μM
IC50
RECORD: Rec_0202945 VERIFIED: NO
Provenance & Taxonomy
Glycine max [Plant]; Fabaceae [Plant]
3847; 3803
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
RECORD: Rec_0204213 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 0.0%, C 100.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0207374 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]
ACE inhibitory peptide
3847
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory Antihypertensive
6.5 μM
IC50
RECORD: Rec_0279526 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
9.4
PaperLin Y.-H., Chen C.-A., Tsai J.-S., Chen G.-W.. Preparation and identification of novel antihypertensive peptides from the in vitro gastrointestinal digestion of marine Cobia skin hydrolysates. Nutrients, 11, 1351, 2019.
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