Peptide Database

Peptide NameRanalexin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC337H558N90O99S5

DescriptionStandard

        MFTLKKSLLLLFFLGTINLSLCEEERNAEEERRDNPDERDVEVEKRFLGGLIKIVPAMICAVTKKC
    

Molecular Weight7614.90 Da

Isoelectric Point (pI)5.41

Net Charge (pH 7.0)-1.51

Net Charge (pH 7.4) -1.79

Charge Density (pH 7.0) -0.0228

GRAVY Index-0.09

Hydrophobic Moment 0.68

Boman Index-0.04

Instability Index43.50

Aliphatic Index 104.85

Aromaticity 0.0606

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3080.88

LogP -23.54

H-bond Donors 109.0

H-bond Acceptors 103.0

Rotatable Bonds 266.0

Heavy Atoms 531.0

Ring Count 6.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0046412 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates catesbeianus [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-positive Cytolytic Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)