Peptide Database

Peptide NameB1-Lys

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC97H166N28O16

DescriptionStandard

        VKRFKKFFRKLKKKV
    

Molecular Weight1980.53 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)8.73

Net Charge (pH 7.4) 8.51

Charge Density (pH 7.0) 0.5818

GRAVY Index-1.05

Hydrophobic Moment 0.95

Boman Index-0.58

Instability Index2.15

Aliphatic Index 64.67

Aromaticity 0.2000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 776.66

LogP -2.30

H-bond Donors 29.0

H-bond Acceptors 25.0

Rotatable Bonds 75.0

Heavy Atoms 141.0

Ring Count 3.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0361231 VERIFIED: YES

Provenance & Taxonomy

OrganismCathelicidin-BF15 C-terminal amidated derivative B3 [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetK562/Adr

Activity5.5 μM

MethodIC50

RECORD: Rec_0362304 VERIFIED: YES