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MYP_137612
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Basic Information
B1-Lys
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
15 amino acids
C97H166N28O16
Standard
Sequence
VKRFKKFFRKLKKKV
Physicochemical Analysis
1980.53 Da
12.00
8.73
8.51
0.5818
-1.05
0.95
-0.58
2.15
64.67
0.2000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
776.66
-2.30
29.0
25.0
75.0
141.0
3.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0077848 VERIFIED: YES
Provenance & Taxonomy
Cathelicidin-BF15 C-terminal amidated derivative B3 [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 25462264 PMID25462264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25462264/
RECORD: Rec_0080105 VERIFIED: YES
Provenance & Taxonomy
Cathelicidin-BF15 C-terminal amidated derivative B3 [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7/ADM
8.6 μM
IC50
PaperPubMed PMID: 25462264 PMID25462264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25462264/
RECORD: Rec_0081511 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Polylysine
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID25462264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25462264/
RECORD: Rec_0292770 VERIFIED: YES
Provenance & Taxonomy
Cathelicidin-BF15 C-terminal amidated derivative B3 [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 25462264 PMID25462264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25462264/
RECORD: Rec_0355454 VERIFIED: YES
Provenance & Taxonomy
Cathelicidin-BF15 C-terminal amidated derivative B3 [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
K562
5.5 μM
IC50
PaperPubMed PMID: 25462264 PMID25462264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25462264/
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