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MYP_137610
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Basic Information
AAEL000598-PA, Aedesin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
36 amino acids
C169H300N48O42
Standard
Sequence
GGLKKLGKKLEGAGKRVFKASEKALPVVVGIKAIGK
Physicochemical Analysis
3676.49 Da
10.54
7.76
7.54
0.2155
-0.02
0.72
0.02
10.50
108.33
0.0278
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1463.94
-11.34
51.0
50.0
135.0
259.0
2.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0217910 VERIFIED: YES
Provenance & Taxonomy
Aedes aegypti [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pseudomonas aeruginosa strains ATCC 17978, Pa1, Pa2, Pat3
1-4 μg/mL
MIC
PaperAedesin: structure and antimicrobial activity against multidrug resistant bacterial strains.
RECORD: Rec_0228903 VERIFIED: YES
Provenance & Taxonomy
Aedes aegypti [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Gram-negative (including drug-resistent): E
PaperPubMed PMID: 17510324 | PubMed PMID: 25162372 PMID17510324;25162372 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17510324/
RECORD: Rec_0233140 VERIFIED: YES
Provenance & Taxonomy
Aedes aegypti [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PaperPubMed PMID: 17510324 | PubMed PMID: 25162372 PMID17510324;25162372 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17510324/
RECORD: Rec_0252685 VERIFIED: YES
Provenance & Taxonomy
Aedes aegypti [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
2 μg/mL
MIC
PMID25162372 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25162372/
RECORD: Rec_0262492 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20120316102A1/en PatentUS 2012/0316102 A1
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