Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length275 amino acids

Chemical FormulaC1378H2176N370O386S16

DescriptionStandard

        MGKASCGCLVHFRQICKMVKKSATSHLEPYLRTLPVTLMVDQIAGIDYSLVGAPQVTSQGLDIPFKGEFFGRNQNSSVPFDAPPIGLPQKHDHMIYFAVSEYAFNTASRVYHQAGQMKFTIQNKHIQNLMKFINLKSAPNWRKQQLRPRCQTSKSMPLTTLVSCFSSGFLLDVLQIPLDFPIQLHTSSFRAIIPQLARMYPNMELELETSPESAPFLTFTPGNVTFMPVMDIQAFALLPKSAGRKPLFQIRASTNISITINVNSSTITGSLATGR
    

Molecular Weight30615.31 Da

Isoelectric Point (pI)9.62

Net Charge (pH 7.0)11.07

Net Charge (pH 7.4) 10.38

Charge Density (pH 7.0) 0.0403

GRAVY Index-0.04

Hydrophobic Moment 0.82

Boman Index0.09

Instability Index43.28

Aliphatic Index 85.13

Aromaticity 0.0909

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14690.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0375418 VERIFIED: NO

Provenance & Taxonomy

OrganismOdocoileus virginianus texanus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria