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MYP_137561
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Basic Information
Aurein-2.4 (Frogs, amphibians, animals)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
16 amino acids
C77H132N18O20
Standard
Sequence
GLFDIVKKVVGTLAGL
Physicochemical Analysis
1629.98 Da
8.59
0.76
0.55
0.0474
1.24
0.57
0.44
-5.94
158.12
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
609.39
-2.91
21.0
21.0
55.0
115.0
1.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0078254 VERIFIED: YES
Provenance & Taxonomy
Ranoidea raniformis [Animal]
116057
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Micrococcus luteus
25 μg/mL
MIC
PaperThe antibiotic and anticancer active aurein peptides from the australian bell frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2.
RECORD: Rec_0097393 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0102566 VERIFIED: YES
Provenance & Taxonomy
Litoria aurea [Animal]
Aurein
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anticancer
Staphylococcus aureus
25 μg/mL
MIC
PaperPubMed PMID: 10951191 | Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance. Peptides. 2004 Jun;25(6):1035-1054. doi: 10.1016/j.peptides.2004.03.006. PMID: 15203252. PMID10951191;15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/
RECORD: Rec_0110733 VERIFIED: YES
Provenance & Taxonomy
Litoria aurea [Animal]
Aurein
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anticancer
Bacillus cereus
25 μg/mL
MIC
PaperPubMed PMID: 10951191 | Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance. Peptides. 2004 Jun;25(6):1035-1054. doi: 10.1016/j.peptides.2004.03.006. PMID: 15203252. PMID10951191;15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/
RECORD: Rec_0114604 VERIFIED: YES
Provenance & Taxonomy
Litoria aurea [Animal]
Aurein
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anticancer
Streptococcus uberis
25 μg/mL
MIC
PaperPubMed PMID: 10951191 | Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance. Peptides. 2004 Jun;25(6):1035-1054. doi: 10.1016/j.peptides.2004.03.006. PMID: 15203252. PMID10951191;15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10951191/
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