Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Ligase

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length156 amino acids

Chemical FormulaC779H1249N221O224S5

DescriptionStandard

        MKLDKNVQRKAFLDMIAYSEGTDNGRQPTKDRGYDVIVGGKLFSDYSKHPGVYVKLNAKLTSSAAGRYQVLEKFAKHYMKQLGLPDFGPASQDKIALQLIRECKALADIDEGRIHEAIRKCRSRWASLPGAGYGQHEQKIEKLIEVFKKAGGIVLD
    

Molecular Weight17454.92 Da

Isoelectric Point (pI)9.45

Net Charge (pH 7.0)7.84

Net Charge (pH 7.4) 7.33

Charge Density (pH 7.0) 0.0503

GRAVY Index-0.51

Hydrophobic Moment 0.74

Boman Index-0.08

Instability Index34.00

Aliphatic Index 83.85

Aromaticity 0.0833

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16055.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7232.67

LogP -66.60

H-bond Donors 252.0

H-bond Acceptors 241.0

Rotatable Bonds 602.0

Heavy Atoms 1229.0

Ring Count 23.0

Amide Bonds 166.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0014775 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia phage APECc02 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Ligase Lyase Cytolytic Non-hemolytic

RECORD: Rec_0228695 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia phage slur12 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic

RECORD: Rec_0282368 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage inoa [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic

RECORD: Rec_0325465 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia phage slur16 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic