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MYP_137535
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Basic Information
22
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
21 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KLXXKXXFXXKXXFXXKXXKR
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0351949 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
tetrahydroisoquinolinecarboxylic acid, B = octahydroindolecarboxylic acid, C terminal -CONH2 at 3,6,9,12,15,18; non-canonical residue code at 4,7,10,13,16,19; tetrahydroisoquinolinecarboxylic acid, B = octahydroindolecarboxylic acid, C terminal -CONH2
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ME/GM/MTC resistant bacteria
PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
RECORD: Rec_0358631 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
tetrahydroisoquinolinecarboxylic acid, B = octahydroindolecarboxylic acid, C terminal -CONH2 at 3,6,9,12,15,18; non-canonical residue code at 4,7,10,13,16,19; tetrahydroisoquinolinecarboxylic acid, B = octahydroindolecarboxylic acid, C terminal -CONH2
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium ranae
PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
RECORD: Rec_0405906 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
tetrahydroisoquinolinecarboxylic acid, B = octahydroindolecarboxylic acid, C terminal -CONH2 at 3,6,9,12,15,18; non-canonical residue code at 4,7,10,13,16,19; tetrahydroisoquinolinecarboxylic acid, B = octahydroindolecarboxylic acid, C terminal -CONH2
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtillis
PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
RECORD: Rec_0415098 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic designed peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium ranae
30 μM
MIC
PatentUS 2012/0197004
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