‹ ›
MYP_137535
← PREVIOUS NEXT → BACK
Basic Information
22
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
not Standard
21 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KLXXKXXFXXKXXFXXKXXKR
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0054981 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
tetrahydroisoquinolinecarboxylic acid, B = octahydroindolecarboxylic acid, C terminal -CONH2 at 3,6,9,12,15,18; non-canonical residue code at 4,7,10,13,16,19; tetrahydroisoquinolinecarboxylic acid, B = octahydroindolecarboxylic acid, C terminal -CONH2
Bio-Activity Profile
Antimicrobial Antibacterial
MIC against Salmonella typhimurium
PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
RECORD: Rec_0127268 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
residue-level stereochemical modification [Mixed]
None
Amidation
Tic- tetrahydroisoquinolinecarboxylic acid, Oic- octahydroindolecarboxylic acid
Bio-Activity Profile
Toxic Hemolytic Antibiotic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0131643 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Tic- tetrahydroisoquinolinecarboxylic acid, Oic- octahydroindolecarboxylic acid
Bio-Activity Profile
Antimicrobial Antibiotic
Mouse erythrocytes
25 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/17547385/ PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
RECORD: Rec_0222068 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Tic- tetrahydroisoquinolinecarboxylic acid, Oic- octahydroindolecarboxylic acid
Bio-Activity Profile
Antimicrobial Antibiotic
Mouse erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/17547385/ PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
RECORD: Rec_0335669 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic designed peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Tic = tetrahydroisoquinolinecarboxylic acid, Oic = Octahydroindolecarboxylic acid
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial Immunomodulatory
Mycobacterium ranae (ATCC 110)
30 μM
MIC
PMID17547385 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17547385/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2