Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length372 amino acids

Chemical FormulaC1856H2922N488O522S10

DescriptionStandard

        AHQHGITVLEKELAHVKLPDISGDTRIKVLGKVHYELSRLDLRSFHLPYSRISLVPNVGLQVSISNAFADMDGNWRVKIHFIRDHGSFHLKVENVYIKINLKLGSDAYGKPTVDTSYCNTRISKVKVHFSGKLGAAITQLRCISLPQVCDIVVKSVHKDLQPYVQTLPVTARVDATTGIDYSLVEPPTASTRSLDAALKGEFFSLANRSTVPFPPLALALPPDHDRMVYFGASSYFFNTAGFAYHAAGALVFEITDAMIPKTVDFHLNTTTFSAFIPQLEEMYPDMLMKFRLSTPSAPFLNVGPGGLSLKPVVDIQAYAILPNSSLAPLFLLSLVSNVSAVINVKSGHIVGSLDVGRMKLSLKHSDVGTFQV
    

Molecular Weight40744.66 Da

Isoelectric Point (pI)8.94

Net Charge (pH 7.0)6.09

Net Charge (pH 7.4) 5.02

Charge Density (pH 7.0) 0.0164

GRAVY Index0.14

Hydrophobic Moment 0.59

Boman Index0.14

Instability Index21.31

Aliphatic Index 101.64

Aromaticity 0.0887

Extinction Coeff. Reduced 23380.00

Extinction Coeff. Oxidized 23505.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0105293 VERIFIED: NO

Provenance & Taxonomy

OrganismSmutsornis africanus (Double-banded courser) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria