‹ ›
MYP_137448
← PREVIOUS NEXT → BACK
Basic Information
Human drosomycin-like defensin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
43 amino acids
C186H310N74O59S7
Standard
Sequence
CLAGRLDKQCTCRRSQPSRRSGHEVGRPSPHCGPSRQCGCHMD
Physicochemical Analysis
4751.37 Da
9.25
4.97
4.52
0.1156
-1.13
0.66
-0.40
125.06
27.21
0.0000
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2158.27
-33.14
83.0
74.0
155.0
326.0
7.0
45.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0315329 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Streptococcus group A
50 μM
MIC
PMID18212107 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18212107/
RECORD: Rec_0329966 VERIFIED: YES
Provenance & Taxonomy
Drosophila melanogaster [Animal]
Defensin
7227
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antifungal
A. nidulans
6.25 μM
MIC
PaperDrosomycin-like defensin, a human homologue of Drosophila melanogaster drosomycin with antifungal activity
RECORD: Rec_0336630 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium solani
25 μM
MIC
PMID18212107 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18212107/
RECORD: Rec_0359123 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Rhizopus oryza
6.25 μM
MIC
PMID18212107 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18212107/
RECORD: Rec_0362834 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antifungal
Filamentous fungi: Aspergillus fumigatus
6.25 μM
MIC
PMID18212107 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18212107/
FIRST PREV 1 ... 5 6 7 8 NEXT LAST
Showing 5 records on this page · Page 7 of 8