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MYP_137436
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Basic Information
Kalata B2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anthelminthic
Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Binding / Molecular interaction ▸ Binding activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
29 amino acids
C122H188N34O41S6
Standard
Sequence
GLPVCGETCFGGTCNTPGCSCTWPICTRD
Physicochemical Analysis
2979.39 Da
4.67
-1.29
-1.59
-0.0446
0.11
0.27
0.16
47.28
36.90
0.0690
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1168.51
-16.68
46.0
46.0
86.0
203.0
6.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0080100 VERIFIED: YES
Provenance & Taxonomy
Oldenlandia affinis [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-19; 9-21; 14-26
Bio-Activity Profile
Insecticidal Hemolytic
Human red blood cells
PaperPubMed PMID: 10600388 | PubMed PMID: 15654741 | PubMed PMID: 17534989 | PubMed PMID: 20564013 PMID10600388;15654741;17534989;20564013 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10600388/
RECORD: Rec_0095573 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Insecticidal
PaperPhytAMP: a database dedicated to antimicrobial plant peptides PMID18836196 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18836196/
RECORD: Rec_0133448 VERIFIED: YES
Provenance & Taxonomy
Oldenlandia affinis [Plant]
Cyclic Peptide
60225
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Cytotoxic Antifungal Nematocidal Anthelmintic Molluscicidal Membrane-Binding Insecticidal Hemolytic Antiviral Antiparasitic Anti-Gram-negative
Escherichia coli
160 μM
MIC
PaperPubMed PMID 2056401 | PubMed PMID 3156547 | PubMed PMID 4000000 | Fensterseifer IC et al., 2014 | Printing M et al., 2010 PMID2056401;3156547;4000000;20564013;15654;74000 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2056401/
RECORD: Rec_0144269 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0149943 VERIFIED: YES
Provenance & Taxonomy
Oldenlandia affinis [Plant]
cyclotide family
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
5-19; 9-21; 14-26
Bio-Activity Profile
Antimicrobial cyclotide family Host defense
PaperPDB 1PT4 structural record; NMR; chain A; residues 5-29
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