Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length113 amino acids

Chemical FormulaC551H875N157O169S9

DescriptionStandard

        MRLLLLALPVLAFLPQVIPAYGGGKKCWNKSGRCRKHCKDGEVAQEICKNHRTCCVPGNKDHERVTKTSSPNRFAASSDFVNFIAMDLIPTTDYLDVDNMNEEDEIQSLYQSS
    

Molecular Weight12691.38 Da

Isoelectric Point (pI)6.80

Net Charge (pH 7.0)-0.28

Net Charge (pH 7.4) -0.77

Charge Density (pH 7.0) -0.0025

GRAVY Index-0.42

Hydrophobic Moment 0.62

Boman Index-0.07

Instability Index46.67

Aliphatic Index 75.93

Aromaticity 0.0708

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5271.04

LogP -56.15

H-bond Donors 185.0

H-bond Acceptors 181.0

Rotatable Bonds 422.0

Heavy Atoms 886.0

Ring Count 18.0

Amide Bonds 123.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0390110 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

FamilyDefensin

Tax ID9986

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence