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MYP_137403
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Basic Information
BacW2R (cyclic derivative of bactenecin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
15 amino acids
C86H154N34O16S2
Standard
Sequence
RRLCRIVWVIRVCRR
Physicochemical Analysis
1984.49 Da
12.00
5.74
5.51
0.3827
0.17
0.68
-0.45
74.39
136.00
0.0667
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
857.91
-5.54
37.0
24.0
66.0
138.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0285197 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus pneumoniae ATCC 49619
8 μg/mL
MIC
PMID10223951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10223951/
RECORD: Rec_0290549 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Corynebacterium xerosis
0.25 μg/mL
MIC
PaperImproved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide. Antimicrob Agents Chemother. 1999 May;43(5):1274-1276. doi: 10.1128/AAC.43.5.1274. PMID: 10223951. PMID10223951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10223951/
RECORD: Rec_0302742 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium 14028s
2 μg/mL
MIC
PaperImproved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide. Antimicrob Agents Chemother. 1999 May;43(5):1274-1276. doi: 10.1128/AAC.43.5.1274. PMID: 10223951. PMID10223951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10223951/
RECORD: Rec_0312079 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 6172185 B1 Evidence URLhttps://patents.google.com/patent/US6172185B1/en PatentUS 6172185 B1
RECORD: Rec_0321266 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
mitis
0.25 μg/mL
MIC
PaperImproved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide. Antimicrob Agents Chemother. 1999 May;43(5):1274-1276. doi: 10.1128/AAC.43.5.1274. PMID: 10223951. PMID10223951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10223951/
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