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MYP_137377
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Basic Information
Phylloseptin-PBa2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C96H154N22O24
Standard
Sequence
FLSLLPHIASGIASLVSKF
Physicochemical Analysis
2000.38 Da
8.76
0.85
0.59
0.0445
1.33
0.49
0.51
38.27
148.95
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
713.95
-4.22
25.0
26.0
63.0
142.0
4.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0080415 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans NCPF 1467
15 μM
MIC
PMID30612735 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30612735/
RECORD: Rec_0174671 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Hemolytic
5 μM
MIC
RECORD: Rec_0190173 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Hemolytic
200 μM
MIC
RECORD: Rec_0284012 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID30612735 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30612735/
RECORD: Rec_0319057 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli NCTC 10418
200 μM
MIC
PMID30612735 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30612735/
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