‹ ›
MYP_137377
← PREVIOUS NEXT → BACK
Basic Information
Phylloseptin-PBa2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C96H154N22O24
Standard
Sequence
FLSLLPHIASGIASLVSKF
Physicochemical Analysis
2000.38 Da
8.76
0.85
0.59
0.0445
1.33
0.49
0.51
38.27
148.95
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
713.95
-4.22
25.0
26.0
63.0
142.0
4.0
18.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0020071 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Hourse red blood cells
2.0 μM
Hemolysis
PMID30612735 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30612735/
RECORD: Rec_0040087 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID30612735 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30612735/
RECORD: Rec_0054826 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Hemolytic
Candida albicans
15 μM
MIC
RECORD: Rec_0060605 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus NCTC 10788
5 μM
MIC
PMID30612735 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30612735/
RECORD: Rec_0062573 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa burmeisteri [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Candida albicans
15 μM
MIC
PaperPhylloseptin-PBa1, -PBa2, -PBa3: Three Novel Antimicrobial Peptides From the Skin Secretion of Burmeister's Leaf Frog (Phyllomedusa Burmeisteri)
1 2 3 NEXT LAST
Showing 5 records on this page · Page 1 of 3