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MYP_137367
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
6 amino acids
C33H49N9O8
Standard
Sequence
GVYPHK
Physicochemical Analysis
699.80 Da
8.60
0.85
0.59
0.1409
-1.03
0.17
0.01
55.80
48.33
0.1667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
274.96
-1.34
9.0
10.0
19.0
50.0
3.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0018865 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0186971 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
1.6 μM
IC50
PaperIsolation and characterization of angiotensin I-converting enzyme inhibitory peptides derived from bonito bowels PMID7764272 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7764272/
RECORD: Rec_0197944 VERIFIED: YES
Provenance & Taxonomy
Actinopterygii [Animal]
7898
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PMID7764272 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7764272/
RECORD: Rec_0280266 VERIFIED: NO
Provenance & Taxonomy
Sarda bowel [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
ACE
1.6 μM
IC50
RECORD: Rec_0290580 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
PaperKaraki H., Kuwahara M., Sugano S., Doi C., Doi K., Matsumura N., Shimizu T.. Oral administration of peptides derived from bonito bowels decreases blood pressure in spontaneously hypertensive rats. Comp. Biochem. Physiol., 104C, 351-.
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