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MYP_137354
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Basic Information
Ple (4-25)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
22 amino acids
C114H176N32O26
Standard
Sequence
SFFKKAAHVGKHVGKAALTHYL
Physicochemical Analysis
2410.82 Da
10.18
3.72
3.35
0.1689
0.00
0.59
0.13
3.39
80.00
0.1364
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
925.23
-6.45
33.0
33.0
79.0
172.0
6.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0221301 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
100 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/20798581/ PMID20798581 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20798581/
RECORD: Rec_0246755 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes (0% Hemolysis at 3.13-100 μM
3.13-100 μM
Hemolysis
PMID20798581;23075787 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20798581/
RECORD: Rec_0319750 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 45.5%, C 54.5% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0344683 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Mammalian Cell
Candida albicans ATCC 90028
PMID20798581;23075787 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20798581/
RECORD: Rec_0380269 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pleurocidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Mammalian Cell
Aspergillus flavus KCTC 1375
20 μM
MIC
PMID20798581;23075787 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20798581/