Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC150H219N41O40S6

DescriptionStandard

        GTRCGETCFVLPCWSAKFGCYCQKGFCYRN
    

Molecular Weight3428.98 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)2.70

Net Charge (pH 7.4) 2.40

Charge Density (pH 7.0) 0.0900

GRAVY Index-0.10

Hydrophobic Moment 0.44

Boman Index0.02

Instability Index9.26

Aliphatic Index 26.00

Aromaticity 0.2000

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1314.69

LogP -13.32

H-bond Donors 53.0

H-bond Acceptors 49.0

Rotatable Bonds 106.0

Heavy Atoms 237.0

Ring Count 8.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0380869 VERIFIED: YES

Provenance & Taxonomy

OrganismLeptopetalum biflorum [Plant],Hedyotis biflora [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Antimicrobial Antibacterial Enzymatic-degradation Anti-Gram-positive

TargetStreptococcus salivarius

Activity5.9 μM

MethodMIC

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