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MYP_137342
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
30 amino acids
C150H219N41O40S6
Standard
Sequence
GTRCGETCFVLPCWSAKFGCYCQKGFCYRN
Physicochemical Analysis
3428.98 Da
8.66
2.70
2.40
0.0900
-0.10
0.44
0.02
9.26
26.00
0.2000
8480.00
8855.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1314.69
-13.32
53.0
49.0
106.0
237.0
8.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029998 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design (https://pubmed.ncbi.nlm.nih.gov/18957441/) PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0066054 VERIFIED: YES
Provenance & Taxonomy
Hedyotis biflora [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
80 μM
MIC
PMID21979955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21979955/
RECORD: Rec_0069247 VERIFIED: YES
Provenance & Taxonomy
Leptopetalum biflorum [Plant],Hedyotis biflora [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antibacterial Enzymatic-degradation Anti-Gram-positive
Staphylococcus epidermidis
80 μM
MIC
PMID21979955;21776960 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21979955/
RECORD: Rec_0069986 VERIFIED: YES
Provenance & Taxonomy
Hedyotis biflora [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID21979955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21979955/
RECORD: Rec_0139843 VERIFIED: YES
Provenance & Taxonomy
Hedyotis biflora [Plant]
Cyclotide
Structure & Mods
Backbone-cyclized cyclotide scaffold with cystine-knot family annotation [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
3.4 μM
MIC
PMID21979955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21979955/
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