Peptide Database

Peptide NameOsteostatin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC152H239N47O50S

DescriptionStandard

        RSAWLNSGMYGSNVTESPVLDNSVTTHNHILR
    

Molecular Weight3556.87 Da

Isoelectric Point (pI)6.92

Net Charge (pH 7.0)-0.06

Net Charge (pH 7.4) -0.37

Charge Density (pH 7.0) -0.0020

GRAVY Index-0.47

Hydrophobic Moment 0.43

Boman Index-0.01

Instability Index91.67

Aliphatic Index 79.06

Aromaticity 0.0625

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1582.61

LogP -20.80

H-bond Donors 56.0

H-bond Acceptors 53.0

Rotatable Bonds 113.0

Heavy Atoms 250.0

Ring Count 6.0

Amide Bonds 35.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0063590 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyOsteostatin

Tax ID9031

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Growth regulation Development regulation Receptor modulation

Half-LifeMammalian: 1 hour; Yeast: 2 min; E. coli: 2 min

RECORD: Rec_0301943 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0362423 VERIFIED: NO

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyParathyroid hormone

Tax ID9031

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone