Peptide Database

Peptide NameChromogranin-A

Function Ontology

Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Standard StatusStandard

Sequence Length448 amino acids

Chemical FormulaC2107H3358N638O767S10

DescriptionStandard

        LPVNSPMTKGDTKVMKCVLEVISDSLSKPSPMPVSPECLETLQGDERVLSILRHQNLLKELQDLALQGAKERAQQQQQQQQQQQQQQQQQQQQHSSFEDELSEVFENQSPAAKHGDAASEAPSKDTVEKREDSDKGQQDAFEGTTEGPRPQAFPEPKQESSMMGNSQSPGEDTANNTQSPTSLPSQEHGIPQTTEGSERGPSAQQQARKAKQEEKEEEEEEKEEEEEEKEEKAIAREKAGPKEVPTAASSSHFYSGYKKIQKDDDGQSESQAVNGKTGASEAVPSEGKGELEHSQQEEDGEEAMAGPPQGLFPGGKGQELERKQQEEEEEEERLSREWEDKRWSRMDQLAKELTAEKRLEGEDDPDRSMKLSFRARAYGFRDPGPQLRRGWRPSSREDSVEARGDFEEKKEEEGSANRRAEDQELESLSAIEAELEKVAHQLQALRRG
    

Molecular Weight50219.67 Da

Isoelectric Point (pI)4.67

Net Charge (pH 7.0)-39.45

Net Charge (pH 7.4) -40.23

Charge Density (pH 7.0) -0.0880

GRAVY Index-1.43

Hydrophobic Moment 0.86

Boman Index-0.32

Instability Index85.70

Aliphatic Index 45.83

Aromaticity 0.0335

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0106730 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyChromogranin/secretogranin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsSer96 Phosphoserine; Ser197 Phosphoserine; Ser294 Phosphoserine; Gly314 Amidation; Ser335 Phosphoserine; Ser395 Phosphoserine; Ser399 Phosphoserine

Bio-Activity Profile

Function

Secretory granule peptide Neuropeptide precursor