‹ ›
MYP_137270
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
not Standard
11 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XGLPPGPPIPP
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0085206 VERIFIED: YES
Provenance & Taxonomy
Chinese water [Animal]; Animalia [Animal]
33208; 33208
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Contains non-standard code J
Bio-Activity Profile
Antihypertensive
PMID4323853 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4323853/
RECORD: Rec_0156458 VERIFIED: YES
Provenance & Taxonomy
Gloydius blomhoffii [Animal]
Bradykinin-potentiating peptide
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Pyroglutamylation
N-terminal pyroglutamyl residue (J)
Bio-Activity Profile
Antihypertensive Bradykinin-potentiating
PaperBradykinin-potentiating peptides from the venom of Agkistrodon halys blomhoffi. Isolation of five bradykinin potentiators and the amino acid sequences of two of them, potentiators B and C. PMID4323853 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4323853/
RECORD: Rec_0250972 VERIFIED: YES
Provenance & Taxonomy
Agkistrodon halys blomhoffi,Gloydius blomhoffi [Animal]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamate
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
4.2 μM
IC50
RECORD: Rec_0395983 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
4.2
PaperKato H., Suzuki T.. Bradykinin-potentiating peptides from venom of Agkistrodon halys blomhoffi. Isolation of five bradykinin potentiators and amino acid sequences of two of them, potentiators B and C. Biochemistry, 10, 972-980, 1971.