Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length631 amino acids

Chemical FormulaC3041H4931N853O897S31

DescriptionStandard

        MLQQDQRPGDSSSLSKHFTHRQTKADSWARMFSLTAEMATSSNAASSVSNIVELKKIFFKFDRIKLEEKLVNKQLPPKRPDIHSVTMSLCCLLILVAVIPMTSGTNPGVKVKLTEKGLEYGRQLGMVSIQQKLKSIKVPDISGKQKVSPIGKVRYSLSNMQIVNVGLPKSAVDLVPGTGVKLSIGNAFISLHGNWRVKYLRVIKDRGSFDLNVKGLTISTSIAVKSDETGRPAVSSVNCAATVGSVSIKFHGGASWLYNLFKKFVNKALRNALQKQICPLVANAVSDLNPHLKTLNVLAKVDKYAEIEYSMVSSPTVSKSSIDLSLKGEFYNIGKHREPPFSPAAFYLPPQVNNMLYIGMSAYTANSAGFAYNTAGALSLYITDDMIPQSSPIRLTTRTFGAFIPQIARRFPGLMMKLLLKTEKAPAVTFEPNNVTIQASAAVTAYAIQPNATLSPLFVLNLETSVSAKVFVSGMRLAGAVTLNKMDLTLRTSYVGDFQHPAIGPQSGCDTQSECNRLGVARRSKCDSFPQREEFVSCGVTCVNRRQVSTTVMSGATRSSTCSLGRVSQCHCLSQGAVTEGSTSQALGVGRQYLHRKHKRSPNLRLNDEISENNDAFIVVTVMIVDMMKSH
    

Molecular Weight68787.87 Da

Isoelectric Point (pI)9.76

Net Charge (pH 7.0)33.45

Net Charge (pH 7.4) 32.31

Charge Density (pH 7.0) 0.0530

GRAVY Index-0.08

Hydrophobic Moment 0.81

Boman Index0.04

Instability Index43.35

Aliphatic Index 88.97

Aromaticity 0.0666

Extinction Coeff. Reduced 38850.00

Extinction Coeff. Oxidized 39600.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0225890 VERIFIED: NO

Provenance & Taxonomy

OrganismScophthalmus maximus (Turbot) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria