Peptide Database

Peptide NamePep27anal5

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC183H230N42O36S

DescriptionStandard

        MWKWFHNVLSSGQLLADKWWAWWYNWW
    

Molecular Weight3626.11 Da

Isoelectric Point (pI)8.28

Net Charge (pH 7.0)0.59

Net Charge (pH 7.4) 0.31

Charge Density (pH 7.0) 0.0217

GRAVY Index-0.43

Hydrophobic Moment 0.54

Boman Index0.28

Instability Index9.84

Aliphatic Index 61.48

Aromaticity 0.3704

Extinction Coeff. Reduced 45490.00

Extinction Coeff. Oxidized 45490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1254.22

LogP 0.90

H-bond Donors 46.0

H-bond Acceptors 39.0

Rotatable Bonds 104.0

Heavy Atoms 262.0

Ring Count 19.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0393177 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus pneumoniae [Bacterium]

FamilyS. pneumoniae

Tax ID1313

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Anticancer Cytotoxic

TargetHL-60

Activity>70 μM

MethodIC50

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