‹ ›
MYP_137230
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
13 amino acids
C78H134N20O17
Standard
Sequence
LLRHVVKILEKYL
Physicochemical Analysis
1624.02 Da
9.70
1.85
1.59
0.1421
0.60
0.82
0.11
44.93
194.62
0.0769
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
612.67
0.06
22.0
20.0
56.0
115.0
2.0
12.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0260808 VERIFIED: YES
Provenance & Taxonomy
Lithobates catesbeianus [Animal]; synthetic construct [Synthetic]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Cytotoxic
SW-1116
50 μg/mL
inhibition assay
PaperWang C et al. Designed synthetic analogs of the alpha-helical peptide temporin-La with improved antitumor efficacies via charge modification and incorporation of the integrin alpha-v beta-3 homing domain. J Pept Sci. 2012. PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0279214 VERIFIED: YES
Provenance & Taxonomy
Lithobates catesbeianus [Animal]; synthetic construct [Synthetic]
Temporins
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
HepG-2 (liver cancer)
50 μg/mL
MTT/MTS assay
PaperWang C et al. Designed synthetic analogs of the alpha-helical peptide temporin-La with improved antitumor efficacies via charge modification and incorporation of the integrin alpha-v beta-3 homing domain. J Pept Sci. 2012. PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0292004 VERIFIED: YES
Provenance & Taxonomy
Lithobates catesbeianus [Animal]; synthetic construct [Synthetic]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Anticancer
human tumor cell panel; integrin alpha-v beta-3-expressing tumor cells
MTT/MTS cell-proliferation and cytotoxicity assay
PaperWang C et al. Designed synthetic analogs of the alpha-helical peptide temporin-La with improved antitumor efficacies via charge modification and incorporation of the integrin alpha-v beta-3 homing domain. J Pept Sci. 2012. PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0297231 VERIFIED: YES
Provenance & Taxonomy
Lithobates catesbeianus [Animal]; synthetic construct [Synthetic]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
MEC (24.15Inhibition ratio at 50 μg/ml)
MTT/MTS cell-proliferation and cytotoxicity assay
PaperWang C et al. Designed synthetic analogs of the alpha-helical peptide temporin-La with improved antitumor efficacies via charge modification and incorporation of the integrin alpha-v beta-3 homing domain. J Pept Sci. 2012. PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0297700 VERIFIED: NO
Provenance & Taxonomy
Rana catesbeiana,Lithobates catesbeianus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer
FIRST PREV 1 ... 4 5 6 7 8 9 NEXT LAST
Showing 5 records · Page 6 of 9