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MYP_137230
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C78H134N20O17
Standard
Sequence
LLRHVVKILEKYL
Physicochemical Analysis
1624.02 Da
9.70
1.85
1.59
0.1421
0.60
0.82
0.11
44.93
194.62
0.0769
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
612.67
0.06
22.0
20.0
56.0
115.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0055064 VERIFIED: YES
Provenance & Taxonomy
Lithobates catesbeianus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
P. vulgaris
16 μM
MIC
PaperEffects of Two Novel Peptides from Skin of Lithobates Catesbeianus on Tumor Cell Morphology and Proliferation
RECORD: Rec_0064974 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
RGD motif conjugation
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37280
RECORD: Rec_0066782 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
HEK-293T
50 μg/mL
Inhibition
PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0071137 VERIFIED: YES
Provenance & Taxonomy
Lithobates catesbeianus [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer
Candida albicans ATCC 10231
31.25 μg/mL
MIC
PaperEffects of Two Novel Peptides from Skin of Lithobates Catesbeianus on Tumor Cell Morphology and Proliferation
RECORD: Rec_0073186 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporins
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
A-549 (lung cancer)
50 μg/mL
MTT/MTS assay
PaperDesigned synthetic analogs of the α-helical peptide temporin-La with improved antitumor efficacies via charge modification and incorporation of the integrin αvβ3 homing domain | https://pubmed.ncbi.nlm.nih.gov/22641352/ PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
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