Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC343H561N109O103S11

DescriptionStandard

        MCVSPRARAGLPMGRLSFLRCSASFREVCERPNGSCQEFCLDSEIHSGRCLDGRPCCLPLMNVPEVDPTTPRVR
    

Molecular Weight8212.51 Da

Isoelectric Point (pI)8.19

Net Charge (pH 7.0)1.53

Net Charge (pH 7.4) 1.13

Charge Density (pH 7.0) 0.0206

GRAVY Index-0.23

Hydrophobic Moment 0.50

Boman Index-0.12

Instability Index47.88

Aliphatic Index 65.81

Aromaticity 0.0405

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3374.72

LogP -39.80

H-bond Donors 126.0

H-bond Acceptors 117.0

Rotatable Bonds 262.0

Heavy Atoms 566.0

Ring Count 12.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004142 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus [Animal]

FamilyDefensin

Tax ID72004

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal