Peptide Database

Peptide NameNRC-03

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC132H232N48O29

DescriptionStandard

        GRRKRKWLRRIGKGVKIIGGAALDHL
    

Molecular Weight2955.56 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.84

Net Charge (pH 7.4) 7.58

Charge Density (pH 7.0) 0.3017

GRAVY Index-0.58

Hydrophobic Moment 0.96

Boman Index-0.27

Instability Index68.95

Aliphatic Index 108.85

Aromaticity 0.0385

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1286.17

LogP -10.36

H-bond Donors 49.0

H-bond Acceptors 38.0

Rotatable Bonds 106.0

Heavy Atoms 209.0

Ring Count 3.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0313039 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyNRC peptides

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer

RECORD: Rec_0323267 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudopleuronectes americanus [Animal]

FamilyPleurocidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetAeromonas salmonicida 99-1

Activity2 μg/mL

MethodMIC

RECORD: Rec_0326725 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudopleuronectes americanus [Animal]

FamilyPleurocidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetS. enterica serovar Typhimurium MS7953s

Activity2 μg/mL

MethodMIC

RECORD: Rec_0330704 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 26.9%, E 7.7%, T 46.2%, C 19.2% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Anticancer Antibacterial Toxic Antimicrobial Antifungal Hemolytic Anti-Gram-positive Anti-Gram-negative

RECORD: Rec_0345702 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudopleuronectes americanus [Animal]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetEscherichia coli UB1005

Activity8 μg/mL

MethodMIC

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