Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length502 amino acids

Chemical FormulaC2461H3859N635O742S10

DescriptionStandard

        MKRFWKINIFTGFLTLFSGLLTTNANPGIRLRFTDKGLQLVDTVAIQLLNEKVKTATIPDISGDADTPVGHISYSLSSVHFNSLSIPSSTFKTDPGVGLTLQISNAQVSLSGNWHYRKDHWPHISDSGSFDLDASGLALSVSAKLGADSTGHPTIATSSCSSSVGDVNIHFHGGASWLYNLFDSYVAGKIKDTLQDKLCQEVSEVINNNAEKELSTFPVKKQIDRYALINYSLVSSPVFNESYLDVFIKGEFQSATDPKEAPFSPVSLPTDSESAKMAYVWLTDYVFNTAGLVYQDAGFLNETVTPSMLPPNFSYPLNTSTFKLIIPKLYLMYPNRPMKLVAHSTLRPTVTTSSSGIALTMTGQVETYAQLENGSFVYTFTMGLNISASVKVAVRQTNVTGHVDSVKVKVSLIKSAIGDISINMKLLQFALDAFADQIIAKQLNKIGDVGFPLPVVDGVQLVNAEVTPGKGFNLIATDVKYSPGKSDATDNRPRGRNKIVIV
    

Molecular Weight54534.42 Da

Isoelectric Point (pI)6.80

Net Charge (pH 7.0)-0.62

Net Charge (pH 7.4) -1.49

Charge Density (pH 7.0) -0.0012

GRAVY Index-0.01

Hydrophobic Moment 0.68

Boman Index0.12

Instability Index30.12

Aliphatic Index 92.79

Aromaticity 0.0916

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51465.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0265099 VERIFIED: NO

Provenance & Taxonomy

OrganismPocillopora damicornis [Bacterium]

FamilyBPI

Tax ID46731

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic

MethodQualitative functional evidence