Peptide Database

Peptide NameKalata B5

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC127H203N35O37S6

DescriptionStandard

        PCGESCVWIPCLTSAVGCPCKSKVCYRN
    

Molecular Weight3004.57 Da

Isoelectric Point (pI)8.46

Net Charge (pH 7.0)1.90

Net Charge (pH 7.4) 1.75

Charge Density (pH 7.0) 0.0678

GRAVY Index0.27

Hydrophobic Moment 0.32

Boman Index0.10

Instability Index19.73

Aliphatic Index 62.50

Aromaticity 0.0714

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1128.72

LogP -12.86

H-bond Donors 46.0

H-bond Acceptors 45.0

Rotatable Bonds 91.0

Heavy Atoms 205.0

Ring Count 6.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028239 VERIFIED: YES

Provenance & Taxonomy

OrganismViola biflora [Plant]

FamilyCyclotide

Structure & Mods

Configcyclic cystine-knot cyclotide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideThree-disulfide cyclic cystine knot

Other ModsHead-to-tail backbone cyclization

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetEscherichia coli TOP10 peptide-expressing strain

Activity4.05 OD_ID (dimensionless)

MethodMeX pooled intracellular peptide-expression growth-inhibition assay (NGS-derived OD_ID at 4.5 h)