Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC348H576N100O86S8

DescriptionStandard

        MKLLSLTLVALLLLSQLTPGDALRCWNLHGRCRQRCSRKEKVYVYCTNGKMCCVKPKFQPKNKPWLL
    

Molecular Weight7793.43 Da

Isoelectric Point (pI)9.93

Net Charge (pH 7.0)10.52

Net Charge (pH 7.4) 10.15

Charge Density (pH 7.0) 0.1570

GRAVY Index-0.15

Hydrophobic Moment 0.59

Boman Index-0.07

Instability Index28.39

Aliphatic Index 95.97

Aromaticity 0.0746

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3021.66

LogP -23.55

H-bond Donors 112.0

H-bond Acceptors 106.0

Rotatable Bonds 261.0

Heavy Atoms 542.0

Ring Count 12.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0402751 VERIFIED: NO

Provenance & Taxonomy

OrganismSpermophilus dauricus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence