Peptide Database

Peptide NameSLAY-screened peptide P2582

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC100H152N26O28S

DescriptionStandard

        LSGCYAPSTHVLHAWEKISV
    

Molecular Weight2198.50 Da

Isoelectric Point (pI)6.91

Net Charge (pH 7.0)-0.07

Net Charge (pH 7.4) -0.40

Charge Density (pH 7.0) -0.0037

GRAVY Index0.28

Hydrophobic Moment 0.47

Boman Index0.26

Instability Index36.35

Aliphatic Index 97.50

Aromaticity 0.1000

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 845.05

LogP -6.88

H-bond Donors 31.0

H-bond Acceptors 31.0

Rotatable Bonds 66.0

Heavy Atoms 155.0

Ring Count 6.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0235098 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/