Peptide Database

Peptide NamePiscidin-2, ecPis-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC251H385N81O61S2

DescriptionStandard

        FFFHIVKGLFHAGRMIHGLVNRRRHRHGMEELDLDQRAFEREKAFA
    

Molecular Weight5577.38 Da

Isoelectric Point (pI)10.70

Net Charge (pH 7.0)3.21

Net Charge (pH 7.4) 2.74

Charge Density (pH 7.0) 0.0697

GRAVY Index-0.53

Hydrophobic Moment 0.66

Boman Index-0.15

Instability Index53.56

Aliphatic Index 72.17

Aromaticity 0.1304

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2311.54

LogP -17.15

H-bond Donors 83.0

H-bond Acceptors 71.0

Rotatable Bonds 190.0

Heavy Atoms 395.0

Ring Count 11.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0280599 VERIFIED: YES

Provenance & Taxonomy

OrganismEpinephelus coioides [Animal]

FamilyPiscidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal

TargetEscherichia coli TOP 10

Activity5 μM

MethodMBC

RECORD: Rec_0284741 VERIFIED: YES