Peptide Database

Peptide NameCathelicidin buCATHL4C

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC126H174N40O18

DescriptionStandard

        RIRFPWPWRWPWWRRVR
    

Molecular Weight2536.99 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.56

Charge Density (pH 7.0) 0.3388

GRAVY Index-1.46

Hydrophobic Moment 0.28

Boman Index-0.42

Instability Index83.05

Aliphatic Index 40.00

Aromaticity 0.3529

Extinction Coeff. Reduced 27500.00

Extinction Coeff. Oxidized 27500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 952.90

LogP -0.18

H-bond Donors 38.0

H-bond Acceptors 24.0

Rotatable Bonds 69.0

Heavy Atoms 184.0

Ring Count 14.0

Amide Bonds 16.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0198624 VERIFIED: YES

Provenance & Taxonomy

OrganismBubalus bubalis [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli

Activity12.5 μM

MethodMIC

RECORD: Rec_0408253 VERIFIED: YES