Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC303H481N83O92S6

DescriptionStandard

        SYFEQKSKAVQFLSVGLSPNWGTNRFKMDGRCEVECLSFEDKIGGCRAELTPLCCKKKKEE
    

Molecular Weight6950.95 Da

Isoelectric Point (pI)8.32

Net Charge (pH 7.0)1.43

Net Charge (pH 7.4) 1.12

Charge Density (pH 7.0) 0.0234

GRAVY Index-0.62

Hydrophobic Moment 0.37

Boman Index-0.15

Instability Index31.30

Aliphatic Index 55.90

Aromaticity 0.0984

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2871.29

LogP -29.18

H-bond Donors 104.0

H-bond Acceptors 100.0

Rotatable Bonds 240.0

Heavy Atoms 484.0

Ring Count 9.0

Amide Bonds 64.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0343141 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus dingo [Animal]

FamilyDefensin

Tax ID286419

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal