Peptide Database

Peptide NameNeurotoxin Tx2-9

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC166H266N44O42S6

DescriptionStandard

        SFCIPFKPCKSDENCCKKFKCKTTGIVKLCRW
    

Molecular Weight3742.55 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)5.40

Net Charge (pH 7.4) 5.09

Charge Density (pH 7.0) 0.1687

GRAVY Index-0.29

Hydrophobic Moment 0.47

Boman Index-0.13

Instability Index6.19

Aliphatic Index 45.62

Aromaticity 0.1250

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1406.28

LogP -11.98

H-bond Donors 55.0

H-bond Acceptors 54.0

Rotatable Bonds 125.0

Heavy Atoms 258.0

Ring Count 7.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0172379 VERIFIED: NO

Provenance & Taxonomy

OrganismPhoneutria nigriventer [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0199036 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 18.8%, T 31.2%, C 50.0% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic